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<br /><br /><h2></h2><br />In rodents, the upper sensitivity can also be related to a shorter plasma half-lifetime of T 4 than in people because of appreciable differences between species in the transport proteins for thyroid hormones. In plasma, the T four half-life is about 12—24 h in rats vs 5—9 days in humans, and the serum levels of TSH are about 25 times larger in rodents than in people.<br /><br /><h4></h4><br />Fifty per cent of survivors were sacrificed 1 week later, and blood and urine samples have been taken. Resorcinol confirmed a focus-dependent improve in labelling index [ 3 H]thymidine , acanthosis, and papillomatosis. After utility of an ointment containing To study the goitrogenic exercise of resorcinol, feminine Wistar rats have been treated twice every day for 28 days by rubbing 6 g of an ointment containing Increased thyroid gland weights 2.<br /><br />Determination of resorcinol conjugates within the h urine samples after 14 days of continuous product therapy showed that a maximal 23 mg 2. Assuming a body weight of sixty four kg IPCS, provides an exposure estimate of zero. In a report primarily based on shopper analysis information Gans, , underneath reasonable maximum-use circumstances i.<br />Hence, an improved biodegradation fee results in reduced risks for the setting. Regarding the effects of resorcinol on aquatic species, the toxicity information set consists of a wide range of species from different trophic levels. Results from exams with different aquatic species from totally different trophic ranges are available for the acute toxicity of resorcinol to aquatic organisms.<br /><br />More usual-use circumstances would end in exposures of about zero. Further particulars were not given.<br /><br /><h1></h1><br />Animals that died confirmed hyperaemia and distension of abdomen and intestine, whereas there have been no gross lesions at necropsy in survivors Flickinger, In another study with CFY rats. Most of the studies are of enough high quality and acceptable for risk characterization functions.<br />Resorcinol is known to kind covalent bonds with haem Sessler et al. Effects on the thyroid gland have been reported each in animal studies and in case-reviews in people. However, there are species differences within the susceptibility to goitrogens.

Revision as of 18:56, 13 March 2020




In rodents, the upper sensitivity can also be related to a shorter plasma half-lifetime of T 4 than in people because of appreciable differences between species in the transport proteins for thyroid hormones. In plasma, the T four half-life is about 12—24 h in rats vs 5—9 days in humans, and the serum levels of TSH are about 25 times larger in rodents than in people.


Fifty per cent of survivors were sacrificed 1 week later, and blood and urine samples have been taken. Resorcinol confirmed a focus-dependent improve in labelling index [ 3 H]thymidine , acanthosis, and papillomatosis. After utility of an ointment containing To study the goitrogenic exercise of resorcinol, feminine Wistar rats have been treated twice every day for 28 days by rubbing 6 g of an ointment containing Increased thyroid gland weights 2.

Determination of resorcinol conjugates within the h urine samples after 14 days of continuous product therapy showed that a maximal 23 mg 2. Assuming a body weight of sixty four kg IPCS, provides an exposure estimate of zero. In a report primarily based on shopper analysis information Gans, , underneath reasonable maximum-use circumstances i.
Hence, an improved biodegradation fee results in reduced risks for the setting. Regarding the effects of resorcinol on aquatic species, the toxicity information set consists of a wide range of species from different trophic levels. Results from exams with different aquatic species from totally different trophic ranges are available for the acute toxicity of resorcinol to aquatic organisms.

More usual-use circumstances would end in exposures of about zero. Further particulars were not given.


Animals that died confirmed hyperaemia and distension of abdomen and intestine, whereas there have been no gross lesions at necropsy in survivors Flickinger, In another study with CFY rats. Most of the studies are of enough high quality and acceptable for risk characterization functions.
Resorcinol is known to kind covalent bonds with haem Sessler et al. Effects on the thyroid gland have been reported each in animal studies and in case-reviews in people. However, there are species differences within the susceptibility to goitrogens.